Large skin reaction from a bite or sting

A large skin reaction involves swelling and redness that spreads away from the site of the bite or sting. It may involve an entire limb or a broad area of the body. A large skin reaction is defined as swelling across two major joints, such as from the elbow to the shoulder.

Signs of a large skin reaction include the following:

  • The reaction is usually at its worst after 48 hours.
  • The reaction may last as long as 7 days.
  • Fatigue and nausea may be present.


Author: Jan Nissl, RN, BSLast Updated: February 1, 2008
Medical Review: William M. Green, MD - Emergency Medicine
Sean P. Bush, MD, FACEP - Emergency Medicine and Envenomation Specialist

© 1995-2008 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
This information does not replace the advice of a doctor. Healthwise disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.

Click here to learn about Healthwise
Click here to learn about Healthwise