Several syndromes involve an abnormal electrical connection
(or bypass tract) between the atria and ventricles of the heart, of which
Wolff-Parkinson-White (WPW) is the most common. The bypass tract allows
electricity in the heart to travel abnormally fast and results in a very rapid
heart rate.
The AV node normally serves as the only electrical
connection between the atria and the ventricles. In WPW and other similar
syndromes, an abnormal connection exists between the atria and ventricles that
allows the electrical impulses that start in the atrium to bypass the AV node,
travel directly to the ventricles, and electrically activate or excite the
ventricles earlier than normal. Thus, these syndromes are often referred to as
preexcitation syndromes.
The abnormal connection usually consists
of a small collection of heart muscle fibers and is known as a bypass tract or
an accessory pathway. Most people with this syndrome can be identified by
looking at their electrocardiogram (EKG, ECG). The electrical abnormality in
WPW produces a particular abnormal pattern on an EKG and is usually recognized
by a physician. On EKG in WPW, the electrical preexcitation of the ventricles
can be seen as an abnormality on the EKG known as a delta wave. In some people
with WPW, the accessory pathway is "concealed" and cannot be seen on an
EKG.
The bypass tract allows for a continuous electrical loop to
form, with one side being the bypass tract and the other being the AV node. The
electrical impulse can continuously cycle in this circuit, stimulating the
heart to beat at rates of 160 to 220 times per minute. This type of arrhythmia
is known as an atrioventricular reentrant tachycardia
and is the most common arrhythmia in people with bypass tracts. Additionally,
people with bypass tracts are more likely to develop atrial fibrillation or
atrial flutter. When they do, the electrical impulses can travel down the
bypass tract and cause the heart to beat at rates in excess of 250 to 300 times
per minute. This may result in fainting (syncope), cardiac arrest, or sudden
death.