Tachycardia: Medication and pacemaker interactions
Medicines for tachycardia that may interact with other medicines and with pacemakers and ICDs Medicine
Important medicine interactions
Effect on pacemakers and ICDs
Amiodarone
- Increases the effect of digoxin and warfarin
At high doses, may increase energy requirements on ICDs Disopyramide
- More potential for side effects when given with phenobarbital, phenytoin, or rifampin
Flecainide
- Increases the effect of digoxin
Ibutilide
- Prolongs the heart's QT interval
Unknown Lidocaine
- More potential for side effects when given with propranolol, metoprolol, or cimetidine
Mexiletine
- Increases the effect of theophylline
- Less effective when given with phenobarbital, phenytoin, or rifampin
Not predictable Procainamide
- More potential for side effects when given with cimetidine, alcohol, or amiodarone
Propafenone
- Increases the effect of digoxin, theophylline, and warfarin
- Less effective when given with phenobarbital, phenytoin, or rifampin
- More potential for side effects when given with cimetidine
Quinidine
- Increases the effect of digoxin and warfarin
- More potential for side effects when given with heparin, verapamil, or cimetidine
- Less effective when given with phenobarbital, phenytoin, or rifampin
Sotalol
- Increases the effect of other beta-blockers
May decrease energy requirements on ICDs
| Author: | Robin Parks, MS | Last Updated: September 17, 2008 |
| Medical Review: |
Caroline S. Rhoads, MD - Internal Medicine
Stephen Fort, MD, MRCP, FRCPC - Interventional Cardiology |
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