Age-Related Macular Degeneration

Medications

Anti-VEGF medicines can slow the vision loss that is linked to wet age-related macular degeneration (AMD). These medicines block a protein that leads to the wet type of macular degeneration. This protein is called vascular endothelial growth factor (VEGF). VEGF causes new abnormal vessels to grow in the eye. The growth of these abnormal vessels leads to macular degeneration.

Anti-VEGF medicines appear to slow the growth of abnormal blood vessels that cause vision loss in wet AMD.⁸ Two examples of anti-VEGF medicines used to treat AMD are bevacizumab (Avastin) and ranibizumab (Lucentis). These medicines are injected into the eye.

Anti-VEGF medicines are also known as VEGF inhibitors.

Go to previous section	Go to top of page	Go to next section
Author:	Jeannette Curtis	Last Updated: August 4, 2009
Medical Review:	Kathleen Romito, MD - Family Medicine Christopher J. Rudnisky, MD, FRCSC - Ophthalmology
© 1995-2009 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.This information does not replace the advice of a doctor. Healthwise disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.